FOLH1 and Familial prostate cancer: To confirm the PSMA-specific cytotoxic activity of 212Pb-ADVC001, we measured the impact of 212Pb-ADVC001 activities (0–60 kBq/mL) on the colony formation capacity, metabolic activity, and cellular growth of prostate cancer cells expressing various levels of PSMA (Supplemental Figs. 1A and 1B; supplemental materials are available at http://jnm.snmjournals.org).