Altered serum levels of MICB in SLE and in active disease in juvenile SLE have been demonstrated.31 32 Altogether, the immunoregulatory and suggested disease-aggravating properties of FLI1 and MICB are in line with data reporting immune activation following BPA exposure in animal SLE models.10, 13. The gene discussed is MICB; the disease is systemic lupus erythematosus.