POLE and acute lymphoblastic leukemia: Similarly, other predicted proteins such as ABCB1, MTR, POLE, and PSMB2 have verified connections with several antibiotics (erythromycin-estolate, roxithromycin), drugs used to prevent lymphoblastic leukemia (cytarabine), some kinase inhibitors (nilotinib, imatinib, dasatinib) which have potential connections with antiviral therapy.