Per standard deviation increase in genetically predicted levels of each protein, the OR of RA ranged from 0.99 (95% CI, 0.995 - 0.996; P = 4.86E-13) for CFB to 1.01 (95% CI, 1.01 - 1.02; P = 1.53E-50) for HLA-DRA. This evidence concerns the gene CFB and rheumatoid arthritis.