For 6 of these genes, a role in inflammatory bowel disease is supported by other criteria: GWAS associations with nearby SNPs (ANKRD55, LPP, PDLIM7), experimental perturbation (CCDC50, VCAM1), association with measured protein levels (IL6, VCAM1), or drug effects (IL6, VCAM1). Here, VCAM1 is linked to inflammatory bowel disease.