While neither SAT nor VAT from the four subjects with obesity significantly altered the expression of Kir2.1 (Figure 3(E,F)) or CD36 (Figure 3(G,H)) compared to untreated control cells, large variances and trends in the data suggest that differences may be present in a larger sample size. Here, KCNJ2 is linked to obesity due to melanocortin 4 receptor deficiency.