Conversely Chit1 is highly expressed in the human lung (Seibold et al. 2008) but has also been shown to be important in the development of bleomycin-induced lung fibrosis and is upregulated in human idiopathic pulmonary fibrosis (Sklepkiewicz et al. 2022). The gene discussed is CHIT1; the disease is pulmonary fibrosis.