Logistic regression analysis demonstrated increased odds of MetS in RA (OR 1.15; 95% CI 1.07, 1.24; p < 0.001) and PsA (OR 1.31; 95% CI 1.13, 1.52; p < 0.001) but decreased odds of MetS in axSpA (OR 0.82; 95% CI 0.70, 0.96; p = 0.012) compared to controls, after adjusting for age, sex, CRP and smoking status (Fig. 1). This evidence concerns the gene CRP and metabolic syndrome.