While we did not directly measure NF‐κB targets in our PN lesions, the overlapping upregulation of NF‐κB‐dependent chemokines and cytokines (e.g., CXCL10, CXCL11, IL1B) in PN lesions suggests a similar inflammatory process may be at play. Here, IL1B is linked to poikiloderma with neutropenia.