Further validation using scRNA‐seq of peripheral blood from patients with acute exacerbation, together with experiments in the experimental autoimmune myasthenia gravis (EAMG) mouse model, suggested that neutrophils may promote plasma cell responses by releasing B‐cell activating factor (BAFF), thereby contributing to acute exacerbation in MG. The gene discussed is TNFSF13B; the disease is myasthenia gravis.