Under the stress of chemotherapy (e.g., cisplatin) or radiotherapy, NF‐κB signaling can activate caspase‐3 and induce apoptosis in tumor cells.[26, 75] Activated caspase‐3 can trigger not only apoptosis but also pyroptosis in tumor cells,[76] positioning caspase‐3 as a crucial molecular switch linking both cell death pathways. Here, NFKB1 is linked to neoplasm.