As a consequence, vinburnine enhances radiotherapy‐induces apoptosis in NPC cells, promotes Gasdermin E (GSDME)‐mediated pyroptosis, and increases the secretion of chemokine (C‐C motif) ligand 5(CCL5) and C‐X3‐C Motif Chemokine Ligand 1 (CX3CL1), which promotes and strengthens T‐cell toxicity against NPC cells. The gene discussed is CX3CL1; the disease is nasopharyngeal carcinoma.