The survival results displayed that high CCL5 (top 25%) with high macrophage infiltration (>50%), high Stat1 (top 25%) with high M1‐type infiltration (>50%) or high Stat1 (top 25%) combined with CCL5 (top 25%) and high M1‐type infiltration (>50%) in tumor tissues indicated better overall survival of patients with ESCA (Figure 8E). This evidence concerns the gene CCL5 and neoplasm.