Prolactin (PRL)-secreting adenomas are pituitary neuroendocrine tumors (PitNETs, also known as pituitary adeno-mas) derived from lactotroph cells and represent more than 30% of all pituitary adenomas and up to 60% of function-al pituitary adenomas both in women and men (1, 2). The gene discussed is PRL; the disease is pituitary gland adenoma.