Kyoto encyclopedia of genes and genome (KEGG) pathway enrichment analysis (Fig. 6B) revealed that upon NUFIP1 KD in Jurkat T cells after LPS stimulation, signaling pathways associated with pathogen infections (Yersinia, Shigella, Salmonella, Escherichia coli, Coronavirus), endoplasmic reticulum protein processing, autophagy, apoptosis, and cGAS-STING signaling were significantly enriched. The gene discussed is CGAS; the disease is infection.