Some studies have shownthat homozygous mice with ATXN1 gene knockout exhibitsimilar aberrations to transgenic mice of the spinocerebellarataxia type 1 (SCA1) model with polyglutamine expansions(Matilla et al., 1998; Crespo-Barreto et al., 2010). Here, ATXN1 is linked to spinocerebellar ataxia type 1.