PNPLA3 and Cirrhosis: As shown in Table 2, compared with NCLD, when adjusted for sex, age, BMI, and ethnicity, patients with the CG-PNPLA3 genotype exhibited a 3.2-fold increase in the odds of developing cirrhosis (OR: 3.208, 95% CI 1.560–6.597, p = 0.002).