Che et al. (2023) also demonstrated that the serine/arginine-rich splicing factor 3 (SRSF3), which is highly expressed in cervical cancer, modulates the alternative splicing of exon 12 in the transcriptional cofactor DEAD-box helicase 5 (DDX5). This splicing alteration leads to an increased production of the pro-oncogenic splice variant DDX5-L and a reduction in the levels of the tumor-suppressive splice variant DDX5-S. Consequently, these changes promote the proliferation, migration, and invasion of cervical cancer CaSki cells (Che et al., 2023). This evidence concerns the gene DDX5 and neoplasm.