VWF and von Willebrand disease (hereditary or acquired): Humate-P is a plasma-derived concentrate containing both vWF and factor VIII, used to treat and prevent bleeding episodes in patients with vWD or hemophilia A. During the case, maintenance of normothermia via a temperature probe, fluid management through an IV fluid bolus, and monitoring of coagulation parameters through a preoperative assessment of coagulation factors for baseline were performed.