FMR1 and fragile X syndrome: During resting-state EEG, individuals with FXS demonstrated a reduction and global leftward shift in alpha, while studies in Fmr1–/– KO mice show conflicting results, with some showing no differences from controls and others demonstrating a decrease in alpha power (Pedapati et al., 2022; Jonak et al., 2024; Kozono et al., 2020).