Among baseline infection characteristics, CRP levels (OR = 1.01; 95% CI, 1.00–1.01; P = 0.008), and fever (OR = 3.11; 95% CI, 1.47–6.71; P = 0.003) were significantly associated with treatment failure, though only fever remained significant in multivariate and adjusted models. The gene discussed is CRP; the disease is infection.