Patients with BDUC had similar levels of transferrin saturation of 24.1% (SD, 10.8%) as healthy controls (mean [SD], 25.4% [10.9%]; Padj = .84), patients with von Willebrand disease (mean [SD], 27.6% [16.7%]; Padj = .146), patients with platelet function defects (mean [SD], 24.0% [10.6%]; Padj = 1.0), or patients with coagulation factor deficiencies (mean [SD], 24.2% [8.6%]; Padj = 1.0). The gene discussed is TF; the disease is complement factor I deficiency.