When taking into account both the amylase > 250 IU/L and CEA > 192 ng/mL cutoff points at the same time to diagnose IPMN cysts, 17 out of 26 patients (65.4%) diagnosed with IPMN in EUS also had the same diagnosis in cyst fluid analysis. This evidence concerns the gene CEACAM5 and pancreatic intraductal papillary-mucinous neoplasm.