A multicenter study in the United States with 120 patients showed that cyst fluid CEA level higher than 192 ng/mL had a diagnostic sensitivity of 75%, specificity of 84%, and diagnostic accuracy of 79% in differentiating mucinous cysts from non-mucinous cysts,4 which compared with the present study, reported higher sensitivity and lower specificity. This evidence concerns the gene CEACAM5 and cyst.