Carcinoembryonic antigen (CEA) and amylase level are the most commonly investigated markers among the various markers.11 However, the effectiveness of biochemical analysis of pancreatic cyst fluid obtained through FNA is still debated.11-13 Some guidelines support EUS-FNA role,14 but others have limited its indications.15 A search in reliable domestic and foreign databases showed that, so far, no study has been conducted in the country regarding the concordance of EUS results and biochemical analysis of fluid obtained from FNA in patients with pancreatic cysts. The gene discussed is CEACAM5; the disease is Pancreatic cysts.