Sensitivity, specificity, positive and negative predictive values of simultaneous amylase > 250 IU/L and CEA > 192 ng/mL cutoff points to diagnose IPMN (taking EUS as the reference) were 65.4%, 45.1%, 53.8%, and 82.1%, respectively (Table 2). Here, CEACAM5 is linked to pancreatic intraductal papillary-mucinous neoplasm.