CGA and irritable bowel syndrome: Instead, they observed a reduced density of CgA-containing cells.9 Furthermore, the study by Mujagic and others showed an increase in CgA density in fecal samples of patients with IBS as compared with controls (23.3 ± 28.5 versus 14.6 ± 15.7, respectively, P = 0.001),14 which represented the colonic CgA concentration.