GPT and COVID-19: Moreover, a prior review has demonstrated that some patients with COVID-19 have hepatic injury manifested as alanine aminotransferases (ALT) and aspartate aminotransferases (AST) elevation that is commonly noticed in severe COVID-19 infections.4 Liver enzyme elevation can be considered a predictive factor for disease course as patients who have significantly elevated levels have higher odds of hospital admission, intensive care unit (ICU) admission, intubation, and death.5