The average age was (68.5 ± 6.2) years, the duration of diabetes was (9.2 ± 4.8) years, the duration of hypertension was (7.8 ± 5.1) years, the baseline glycated hemoglobin was (8.89 ± 2.3)%, the average number of daily medications was (5.3 ± 1.8) types, and the average daily insulin injection volume was (38.2 ± 12.7) units. The gene discussed is INS; the disease is Hypertension.