The nomogram model incorporating these five predictors demonstrated AUC values of 0.902 (training cohort), 0.935 (internal validation), and 0.936 (external validation), exceeding the predictive capacity of individual variables: stroke type (AUC = 0.642), age (AUC = 0.756), albumin level (AUC = 0.754), leukocyte count (AUC = 0.712), and ADL score (AUC = 0.839). This evidence concerns the gene ALB and Stroke.