F2R and atherosclerosis: Moreover, the rs1801719 C/T polymorphism located in the 3′untranslated region (3′UTR) of PAR-1 influences microRNA binding sites, potentially regulating PAR-1 gene expression and modulating interactions with microRNAs, which may have important implications in the context of atherosclerosis (Zhou et al., 2009; Alkozi et al., 2017; Cañadas-Garre et al., 2019).