This peptide is composed of 3 amino acids with an Arg-Gly-Asp motif and has specificity for the integrins αvβ3 and αvβ5 overexpressed by cancer cells and in particular in HNCs.14,15 Otherwise, the overexpression of epidermal growth factor receptor (EGFR) is probably the most relevant target for these cancers. Here, EGFR is linked to cancer.