Consistent with these findings, analysis of GEO transcriptomic sequencing datasets (accession numbers: GSE9484, GSE115193) revealed that PPARγ was compensatorily upregulated in early‐stage NAFLD but downregulated in late‐stage disease (Figure 1A,B) (Qiu et al. 2023). Here, PPARG is linked to metabolic dysfunction-associated steatotic liver disease.