XBP1 and type 2 diabetes mellitus: We found a strong posterior probability that the same locus is associated with T2DM risk and XBP1 expression in East Asians (islets = 1%, pancreas 5%) (Fig. 1a), while weaker probabilities were observed in white Europeans (islets = 0.3%, pancreas = 0.55%) using the eCAVIAR method.