Similar to our spatial analyses, single-cell RNA profiling analysis of 6 patients with triple-negative breast cancer extrapolated from the report by Karaayvaz et al. (53) indicated that cells annotated as malignant, based on marker genes and inferred copy number aberrations, had significantly higher expression of USP10 compared with epithelial cells (Figure 7, A and B, and Supplemental Figure 14, A–C). The gene discussed is USP10; the disease is triple-negative breast carcinoma.