Correlation analysis between SOX2 and these 12 transcription factors in GSCs using sequencing data from our internal glioma database and the GSE67089 database revealed that only Y‐box binding protein 1 (YBX1) met the criteria of Pearson r > 0.8 and p < 0.05 in both databases, indicating a strong positive correlation between YBX1 and SOX2 in GSCs (Figure 5B; Figure S6B, Supporting Information). This evidence concerns the gene YBX1 and central nervous system cancer.