BackgroundAlzheimer's disease (AD) and stroke, both of which are age-related conditions, exhibit common risk factors such as hypertension, smoking, diabetes, and the <i>APOE</i> ε4 genotype, which frequently coexist in older adults.ObjectiveThis study investigates disparities in stroke-related mortality among AD patients, categorized by sex, race/ethnicity, and geographic region.MethodsThe age-adjusted mortality rates (AAMRs) per 100,000 for adults 65 and older were sourced from the CDC WONDER database using ICD codes for AD (G30) and stroke (I60-I61, I63-I64, I69). The gene discussed is APOE; the disease is stroke disorder.