FOXP3 and colorectal cancer: Few studies have reported the association between O. splanchnicus and disease, but mono‐colonization with O. splanchnicus has been shown to suppress inflammation in colitis mice by inducing Foxp3+/RORγt+ Tregs.[15] Xing et al.[16] observed abundant enrichment of O. splanchnicus in Tak1∆M/∆M mice, with an evident induction of Th17 cell development following O. splanchnicus intervention, which protected against colitis and colorectal cancer.