Impaired autophagic pathways have previously been reported in lung epithelial cells of IPF patients.[22, 23] Our scRNA‐seq analysis further revealed significant decreases in autophagy‐related proteins, including ULK1, Beclin1, LC3B, and STX17, specifically in AT2 cells of IPF patients (Figure7A–C; Figure S12A–D, Supporting Information). Here, STX17 is linked to idiopathic pulmonary fibrosis.