The association between neuropsychiatric, cardiovascular, and sensory impairment/cancer clusters and dementia was notably stronger in the group with high CRP levels, with HRs of 2.69 (95% CI: 1.19–6.09), 2.34 (95% CI: 1.08–5.09), and 1.92 (95% CI: 1.02–3.63), respectively. The gene discussed is CRP; the disease is Somatic sensory dysfunction.