When analyzing the plasmablast population, RUNX1 expression remained relatively similar across different MM stages, with MFI values recorded as follows: stage 0 (340 ± 22), stage 1 (331 ± 49), stage 2 (328 ± 41), and stage 3 (277 ± 18), but consistently elevated when compared to healthy controls (173 ± 11) in bone marrow (Figure 4E). Here, RUNX1 is linked to Miyoshi myopathy.