PEComas are also characterized by specific transcriptomic features of the overexpressed DAPL1, MLANA, SULT1C2, GPR143 and CHI3L1 genes, as well as epigenetic features of lysosomal and melanocyte proteins as biomarkers (15). The gene discussed is DAPL1; the disease is neoplasm with perivascular epithelioid cell differentiation.