PEComas are also characterized by specific transcriptomic features of the overexpressed DAPL1, MLANA, SULT1C2, GPR143 and CHI3L1 genes, as well as epigenetic features of lysosomal and melanocyte proteins as biomarkers (15). This evidence concerns the gene SULT1C2 and neoplasm with perivascular epithelioid cell differentiation.