Considering that the tumor was not sensitive to chemoradiotherapy, our patient in this case was in a locally advanced stage with a high recurrence and metastasis rate, along with the patient’s advanced age and frailty, and the positive PD-L1 expression indicated by genetic testing, we opted for a treatment regimen similar to that used for pulmonary sarcomatoid cancer (22). Here, CD274 is linked to neoplasm.