TPRN and sensorineural hearing loss disorder: In addition, ADGRV1, COL2A1, COL4A4, KARS1, LARS2, MYH14, OTOF, TNC, and TPRN have been described for several forms of dominant and recessive hearing loss according to OTOscope v9, and 19 additional genes have been associated with SNHL in HPO.