In doxorubicin-induced DCM rat models, decreased expression was observed for long non-coding RNA (lncRNA) AC061961.2, β-catenin, axis inhibition protein 2 (Axin2), cellular myelocytomatosis oncogene (c-Myc), and B-cell lymphoma-2 (Bcl-2), while levels of Bip, CHOP, caspase-3, and Bax were elevated. This evidence concerns the gene DDIT3 and familial dilated cardiomyopathy.