SQSTM1 and arrhythmogenic right ventricular cardiomyopathy: Studies in ARVC murine models reveal key pathogenic mechanisms: autophagy markers microtubule-associated protein 1 light chain 3 (LC3) and sequestosome 1 (SQSTM1/p62) are significantly overexpressed in cardiomyocytes bordering inflammatory/fibrotic zones, with characteristic autophagic vacuole formation.