CST3 and renal hypertension: We observed positive associations between CLR levels and disease activity (SLEDAI), inflammation (ESR), renal damage indicators (BUN, Scr, cystatin C, blood/urine α1-MG, blood/urine β2-MG, URBC, 24h-UTP, and renal hypertension), systemic involvement (hematological/cardiac involvement and serositis), autoantibodies (AHA, AnuA, anti-dsDNA, and anti-rRNP), and pathological parameters (AI score, endocapillary hypercellularity, and pathological type).