In the cohort of Cano et al. (14) mean HbA1c in WS1 patients was 7.72 ± 0.21 vs. 8.99 ± 0.25% in persons with T1DM, P = 0.002, while the mean insulin requirement was 0.71 ± 0.07 vs. 0.88 ± 0.04 UI * kg * day, respectively, P = 0.0325. The gene discussed is INS; the disease is type 1 diabetes mellitus.