2023). Previous studies have identified AIP as a strong predictor of adverse cardiovascular outcomes (G. Cai et al. 2019; Qin and Chen 2024), with significant associations observed for intracranial arterial stenosis (Yu et al. 2024) and ischemic stroke (Y. Zhang et al. 2024). However, most investigations have relied on single‐time‐point measurements of AIP. In comparison, cumulative AIP (CumAIP) may better reflect the long‐term impact of lipid dysregulation on stroke risk (Z. Liu et al. 2024). The gene discussed is AIP; the disease is ischemic stroke.