We identified 18 overlapping mRNA between POAG and AD including MYH14, EFNA1, FZD1, CACNG3, LTBP3, DIAPH2, GADD45B, ELF3, CRLF1, KCNJ2, SLC24A3, GP1BB, GRP, SLC25A10, ATP6AP2, SCARF2, LLGL2, and CST3 (Fig. 4C). The gene discussed is LLGL2; the disease is open-angle glaucoma.