We identified 18 overlapping mRNA between POAG and AD including MYH14, EFNA1, FZD1, CACNG3, LTBP3, DIAPH2, GADD45B, ELF3, CRLF1, KCNJ2, SLC24A3, GP1BB, GRP, SLC25A10, ATP6AP2, SCARF2, LLGL2, and CST3 (Fig. 4C). Here, EFNA1 is linked to Alzheimer disease.