We identified 18 overlapping mRNA between POAG and AD including MYH14, EFNA1, FZD1, CACNG3, LTBP3, DIAPH2, GADD45B, ELF3, CRLF1, KCNJ2, SLC24A3, GP1BB, GRP, SLC25A10, ATP6AP2, SCARF2, LLGL2, and CST3 (Fig. 4C). Here, CRLF1 is linked to open-angle glaucoma.