Analogous to photodegradation-targeting chimeras, TYRP1-targeted photosensitizer conjugates encapsulated in nanoplatforms (e.g., via TYRP1 ligand-photosensitizer linkers) may enable tumor-specific spatiotemporal killing.[40] These strategies leverage TYRP1’s restricted expression to enhance specificity and efficacy. This evidence concerns the gene TYRP1 and neoplasm.