Moreover, irregular tumor margin, ill-defined pseudo-capsule and longer T1 relaxation time were found to be strongly correlated with the high Ki-67 pattern of HCC, with sensitivity, specificity and diagnostic accuracy ranging from 0.79 to 0.91, 0.67 to 0.90, and 0.78 to 0.93, respectively [33–35]. The gene discussed is MKI67; the disease is hepatocellular carcinoma.