In this study, we clarified that Serum AFP > 20 ng/mL, PVP hypo/marked hypo-enhancement, tumor MeanLin ratio ≥ 3.96 and margin MeanLin ratio ≥ 1.43 were independent predictors for MTM subtype, whereas age < 59 years, AFP-L3% > 10 U/mL, tumor MeanLin ratio ≥ 2.98 and margin WiPI ratio ≥ 2.55 were independent predictors for high Ki-67 pattern. This evidence concerns the gene MKI67 and neoplasm.