CASP1 and type 2 diabetes mellitus: When different concentrations of MCC950 were administered to the vitreous cavity of T2DM rats, the release of the inflammatory factors, Caspase-1, Cleaved-Caspase-1, IL-1β, and IL-18, was reduced to varying degrees and reached a minimum at a concentration of 1 mM(Fig. 5G-K).