The treatment with EF-24 induced a significant multifold change in the relative expression levels of various genes; notably, many of these induced genes, including FTL, UBC, FTH1, UBB, SQSTM1, JUN, MLLT1, GADD45A, KLF6, PPP1R15A, TSPYL2, SRGN, SRXN1, NDRG1, and ZFP36, function as tumor suppressors. The gene discussed is PPP1R15A; the disease is neoplasm.