The analysis indicated that the genes MAFA, CLU, RHOB, RASD1, HSPA1B, HSPA1A, HMOX1, CXCL8, DNAJB1, NCF2, SAT1, IER5, BAG3, B4GALNT1, CCL3, ANXA2, PPP1R15A, CES1, and JUN, which were induced in EF-24–treated cells (Fig 5B), may participate in cancer progression [17,21–23]. This evidence concerns the gene ANXA2 and cancer.