Elevated expression of beaded filament structural protein 1 (BFSP1) in hepatocellular carcinoma facilitates tumor invasiveness and aerobic glycolysis, with METTL3-mediated m6A methylation of BFSP1 mRNA enhancing its post-transcriptional stability through a YTHDF1-dependent mechanism, thereby augmenting BFSP1-driven oncogenic functions [173]. The gene discussed is METTL3; the disease is hepatocellular carcinoma.